Absolute and relative contraindications to IVF

Absolute and relative contraindications to IVF

For successful in vitro fertilization in the preparatory stage, specialists need full information about the state of health of future parents. It helps to identify absolute and relative contraindications to the procedure.

The first are not so categorical obstacles, conditions that can interfere with embryo engraftment and bearing a child. They can be cured - and IVF will end successfully.

Relative contraindications to the procedure are:

  1. Benign tumors of the female genital organs. An obstacle to the procedure is a myoma node larger than 30 mm. If the myoma is located on the front wall of the uterus, and the replanting will be carried out on the back, then such nodes do not represent a threat. Removal of large nodes with laparoscopy takes time to restore the female reproductive organ, and in this case, a transplant can only be done after a year.
  2. Infectious diseases. It is impossible to carry out manipulation if one of the patients has active forms of tuberculosis, syphilis, acute infectious diseases and HIV. Only after their complete cure, the doctors will carry out the procedure.
  3. Chronic diseases in the acute stage. It can be an exacerbation of rheumatism, peptic ulcer of the stomach. IVF is carried out after the onset of remission.

Absolute contraindications to such a procedure make it generally impossible. If they are identified, the pair is offered a surrogate motherhood or the adoption of a child.

The absolute contraindications include: malformations of the uterus, its congenital or acquired absence; cancer in women; diseases in which pregnancy and childbirth are generally contraindicated.

If we talk about the developmental defects of the uterus, it is hypoplasia, that is, a childless undeveloped uterus or an organ with a transverse septum (bicorneal). Also, a woman can not bear and give birth to a child with a complete absence of this organ (aplasia). This happens because of the removal of the uterus after tumor diseases, ruptures in childbirth or injuries.

With regard to malignant neoplasms, with cancer of the reproductive organs or its localization elsewhere, the procedure of IVF is prohibited. If a woman has been treated and it was successful, then in vitro fertilization is possible after consultation with an oncologist.

The presence in the future mother of common diseases that pose a threat to life, accompanied by serious complications, is also an absolute contraindication to manipulation. Among such ailments are lymphomas, leukemia, hemolytic anemia, lymphogranulomatosis, heart and vascular malformations, severe forms of hypertension and cardiomyopathy, diabetes mellitus with kidney damage. In addition to these, there are also mental illnesses among women that do not allow them to become mothers. These include severe schizophrenia, uncontrolled psychoses, multiple sclerosis, depression with suicidal tendencies. In such cases, reproductologists suggest that a man and a woman should think about other ways to become parents.

Sometimes IVF may be performed with donor cells. This is possible with the consent of the couple, in the presence of future parents of hereditary diseases. We are talking about neural amyotrophy, hemophilia, ichthyosis. It is proved that the genetic analysis of embryos in such a pair does not give a 100% guarantee for the birth of healthy offspring. Therefore, donor spermatozoa or oocytes are used. However, sometimes the couple does not accept this method because of religious beliefs.

Extracorporeal insemination is a life-saving chance for many desperate to have children of their spouses. But it is not always available.

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