Loperamide is an antidiarrheal agent that reduces motor and tone of the intestinal musculature. The effect of the drug is observed, obviously, due to contact with opioid receptors of intestinal walls. Loperamide reduces peristalsis of the intestine and thereby prolongs the progress of food on it. Another effect of the drug is to increase the tone of the anal sphincter. The drug Loperamide lasts from 4 to 6 hours.
The active substance of the drug is loperamide hydrochloride. Usually, the drug is released in capsules of 2 mg and tablets of the same dosage.
Feature of the drug is the property of almost completely removed from the body by the intestine. However, a small part of Loperamide is excreted by the kidneys. The absorption of the drug is 40%.
Indications for the use of this medicine by a healthy person are chronic and acute diarrhea of ??various nature. Very often Loperamide normalizes the stool of patients with ileostomy.
As for the dosage of the drug, it is taken in without chewing, with enough water. Adults are prescribed first 2 capsules, and then one capsule of Loperamide. The maximum dose of medication per day is 8 capsules for an adult, for children - 3. After normalization of the stool, the medication should be stopped.
You need to know about the side effects of the drug. These are allergic reactions, drowsiness or insomnia, dizziness and intestinal colic, abdominal discomfort and nausea, vomiting and urinary retention.
Contraindications to the use of this drug are diverticulosis, intestinal obstruction, exacerbated ulcerative colitis. Do not use Loperamide for dysentery and gastrointestinal infections. Do not prescribe this medicine to preschool children.
Loperamide during pregnancy: instruction
From the state of health of a pregnant woman, a competent approach to treatment depends on the correct formation and development of the fetus. You should know that during pregnancy, a lot of medicines are excluded from the prescriptions. The reason for this is the presence in their composition of substances that pose a threat to the health of the future child.
As for the drug Loperamide, it is recommended to take it in case of acute necessity. With special care, the drug is prescribed in the first trimester of pregnancy, and it is rather an exception to the rules. To avoid complications, it is better to exclude this drug in the presence of other methods of treatment of diarrhea.
The instruction for this drug clearly states that Loperamide is contraindicated to future mothers in the first trimester. In the 2nd and 3rd trimesters, this medicine is allowed only when the expected benefit exceeds the likelihood of risk for the baby's future.
It is important to take into account the fact that there is no information about the penetration of Loperamide in breast milk during the period of feeding.
So, this medicine is not safe during childbearing, its use is fraught with a threat to the child. But not everything is so terrible. The future mother should understand for herself two postulates: first, under no circumstances to panic, and secondly, to every medicine there is an alternative in folk medicine. Do not just grab for pills with diarrhea, try to cook a rice broth or just eat a few spoons of rice porridge or oatmeal. Good consolidating properties have a decoction of oak bark and walnut. These remedies are absolutely harmless for pregnant women. So try to fix the problem with their help and do not worry.