Lupus anticoagulant during pregnancy

Lupus anticoagulant during pregnancy

What is a lupus anticoagulant

Lupus anticoagulant (BA) is a specific antibody in the blood against phospholipids (blood enzymes). His terrifying name, he received because the first time was found in the blood of people who fell ill with lupus erythematosus.

There are certain norms for the presence of this substance in the blood. This is an indicator in the range of 0, 8-1, 2 conventional units. If the increase in this indicator is diagnosed, then it is fraught with a thrombosis for a person. After all, an increase in the blood quantity of lupus anticoagulants is their attachment to the walls of blood vessels, entry into the blood coagulation reaction and the onset of thrombosis.

Increase in the norm of VA is a characteristic sign of the development in the body of antiphospholipid syndrome (APS). This syndrome has various manifestations in the body. Vascular network on the skin, ulcers on its surface and even necrosis of small areas of skin on the fingers can be manifestations of antiphospholipid syndrome. If the lesion of the vessels with APS is small, then the lesion of the corresponding organ can be insignificant. When it is significant, it can cause chronic diseases, for example, Alzheimer's disease or liver cirrhosis. Very often antiphospholipid syndrome is the main cause of myocardial infarction in people under the age of forty.

An increase in the rate of lupus anticoagulant in the blood can be a complication of medical therapy and the consequence of the use of certain medications.

From all of the above, it follows that an elevated lupus anticoagulant is the first alarming "bell" about serious problems in the body.

How the lupus anticoagulant is diagnosed in pregnant women

During the gestation of the baby, the woman takes many tests, undergoes various examinations to identify and prevent possible violations of the development of the fetus. One of the analyzes - a coagulogram - diagnoses the ability of the blood to coagulate and the characteristics of coagulation in a woman. At normal course of pregnancy blood coagulability raises. So the body of the future mother is preparing for childbirth and the impending loss of blood. Coagulogram is done in the morning on an empty stomach. One of its indicators is a lupus anticoagulant. Its increased norm in pregnant women, as well as in healthy people, is fraught with problems for health.

How does a lupus anticoagulant affect a baby's bearing

An elevated index of this substance in the blood of pregnant women affects the properties of the blood. In this case, the placenta will be at risk of developing thrombosis of the arteries, which may well lead to fetal death in the womb or premature birth.

At best, the influence of lupus anticoagulant on the bearing of a child is manifested in gestosis, that is, complications in the form of edema, increased pressure, the appearance of protein in the urine.

In 27-42% of women with habitual miscarriage of pregnancy, antiphospholipid syndrome is detected. Medical statistics show that with APS in pregnant women up to 80%, the incidence of complications in bearing and childbirth increases. And if you do not carry out the appropriate treatment, the fetal death occurs in 90-95% of expectant mothers.

That's why in order to avoid serious consequences pregnant women need to strictly follow all the prescriptions of the attending physician, clearly follow the prescribed course of treatment.

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