Normogonadotropic anovulatory infertility

Normogonadotropic anovulatory infertility - causes and treatment

The problem arises from a disease of the thyroid gland or gonads. It is known that these glands are responsible for the normalization of the menstrual cycle. In connection with the slightest irregularity of the glands, hormonal failures in the body are possible. Anovulatory normogonadotropic infertility is characterized by the absence of ovulation in women of childbearing age. Sometimes ovulation occurs, but it is very rare or it is not completely full. Why is this happening? Where lies the reason for the absence of ovulation? The main cause of the disease is a decrease in the secretion of gonadotropic hormones, which are responsible for stimulating the growth of follicles with ovules. The disease can be caused by a complication after the transfer of chronic diseases, frequent stressful situations, a sharp decrease in weight, and hereditary predisposition.

In this regard, there is endocrine (anovulatory) infertility, the causes of which can be:

  1. Disorders in the pituitary and hypothalamus. The woman has weight loss, bleeding, depression.
  2. Excess estrogens for the symptom of polycystic ovaries.
  3. Ovarian depletion. The chances of getting pregnant with this diagnosis are zero.
  4. Abnormal phenomena in the chromosomes of the egg.
  5. Congenital hyperfunction of the adrenal cortex.
  6. Thyroid dysfunction.
  7. Diseases of the liver.
  8. Early menopause.
  9. Hypothyroidism and hyperprolactinemia, but in very rare cases.

Treatment of the disease

First of all, the work of endocrine glands should be normal. If anovulation is chronic, then you need to eliminate the dysfunction of not only the endocrine glands, but also bring the endometrium and the fallopian tubes to normal. These disorders occur during the long-term imbalance of the hormonal sphere. Therefore, it is very important to immediately seek medical help when the first signs of ovulation failure appear.

If the cause of endocrine disorders is overweight or, conversely, its lack, then a special diet is needed to adjust the weight.

It is not bad hormonal infertility caused by hyperprolactinemia. This is when the blood of the patient has an increased content of the hormone prolactin. Symptoms of the disease are disorders of the menstrual cycle, allocation of mammary glands colostrum or milk. In these cases, doctors resort to the help of hormonal drugs. Sometimes treatment requires surgical intervention.

80% of women with polycystic ovary syndrome successfully undergo hormonal infertility treatment, but sometimes they have to resort to surgery. It consists of wedge resection of the ovaries or cauterization (electro-or thermocoagulation of the ovaries). These methods lead to a decrease in the body's level of androgens. After that approximately in 70% of women the menstrual cycle is restored and there is a high-grade ovulation.

The stage of stimulation of ovulation should occur under the strict supervision of a doctor and is a serious therapy that is accompanied by frequent ultrasound. Treatment is carried out by hormonal preparations, which are selected by a doctor, taking into account the individual characteristics of the woman's body, and have contraindications and side effects.

Clomiphene citrate (clomid) is used to stimulate ovulation, which promotes the production of follicle-stimulating hormone in the body. Sometimes stimulation of ovulation is carried out not by hormonal preparations, but by physical methods: electrostimulation of the cervix and diencephalic region.

If a woman has ovaries exhausted, the stimulation of ovulation will not help here. In this case, you should resort to the IVF method (artificial insemination). Transplantation into the uterus of the already fertilized egg under the further control of the doctor allows a woman with endocrine problems to give birth to the coveted baby.

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