Many women after taking the drug, the question arises whether pregnancy after Buserelin is possible, the answer to which is not so simple.
As already mentioned, Buserelin is an antitumor drug, a synthetic analogue of GnRH. Its main effect is that it causes a short-term increase in the level of sex hormones in the blood plasma. Approximately after two weeks of using the drug in therapeutic doses, there is a blocking of the secretion of pituitary hormones (the brain's lower appendage), which stimulate the development of the sexual glands (gonads). As a result, the synthesis of sex hormones in the gonads is suppressed.
In women, this is manifested by a decrease in the concentration of female sex hormone in the blood plasma to post-menopausal values, and in men - a decrease in the content of the male sex hormone to postcastrational level.
The drug lasts at least 6 months, it stimulates the state of menopause, resulting in a complete change in the hormonal background of the woman.
Buserelin: side effects and pregnancy
The use of Buserelin is often accompanied by a number of symptoms that are characteristic of climacteric syndrome (hot flushes, dryness of the vaginal mucosa, decreased sexual energy, sleep disturbances, instability emotional states, irritability).
Such symptoms are temporary and usually take place within one week after the end of the course of treatment.
It is also necessary to know, that in women in artificial menopause calcium is actively washed out, which affects the condition of bones. Therefore, during the application of Buserelin, back pain is also possible.
After hormone drug withdrawal, the initial levels of hormones of the reproductive system are restored after 1, 5-2 months. Already in 3-6 months after the end of the course of therapy, stabilization of the process should begin and the monthly recovery should be restored. Control the condition of the internal genitalia with ultrasound. If a woman has endometriosis (foci of the endometrium of the uterus, located in areas unusual for them) and she wants to become pregnant, then this time is most suitable for her. After all, endometriosis, if left untreated, can grow and develop after some time after treatment with Buserelin, and during pregnancy the symptoms of endometriosis disappear.
In other cases, the onset of pregnancy after Buserelin depends on how quickly the body and, in particular, the woman's reproductive system, and her psychological readiness to become pregnant after such a difficult treatment is restored.