The norm of prolactin in women

The norm of prolactin in women

One of the most important hormones, on the concentration of which the woman's ability to conceive depends on is the hormone prolactin. It is this hormone, in the first place, responsible for normal lactation (apparently, this also explains the very name of the hormone mentioned). And, if its elevated levels after the birth of a baby - not only in the order of things, but are welcomed, then here is hyperprolactinaemia at the stage of pregnancy planning makes the conception process impossible and becomes an occasion for mandatory adequate treatment. Without which a positive result - a successful conception - to normalize the levels of prolactin in the body - will have to be forgotten.

Prolactin - get acquainted closer

The hormone prolactin is one of those hormones that are produced by the pituitary gland, one of the brain regions. In small amounts, prolactin is also synthesized by the placenta, ovaries and endometrium. The main function of prolactin against women is the preparation of the mammary glands for the forthcoming pregnancy and the successful delivery of lactation. The development of prolactin is directly related to the formation in the female body of another hormone, estrogen: when the levels of estrogen rise in the body against a background of pregnancy, the body begins to synthesize prolactin in large amounts, Preparing the mammary glands for the upcoming breastfeeding.

Increasing the concentration of prolactin, in turn, "slows down" the production of another hormone, progesterone. During lactation, suppression of progesterone production and prolactin blockade of the synthesis of hormones responsible for ovulation significantly reduces the likelihood of re-conception. What, in fact, explains the impossibility of pregnancy on the background of breastfeeding, if the female body is working normally.

Some increase in the levels of prolactin in the body can be observed and by some During lactation, suppression of progesterone production and prolactin blockade of the synthesis of hormones responsible for ovulation significantly reduces the likelihood of re-conception. What, in fact, explains the impossibility of pregnancy on the background of breastfeeding, if the female body is working normally.

Some increase in the levels of prolactin in the body can be observed and by some During lactation, suppression of progesterone production and prolactin blockade of the synthesis of hormones responsible for ovulation significantly reduces the likelihood of re-conception. What, in fact, explains the impossibility of pregnancy on the background of breastfeeding, if the female body is working normally.

Some increase in the levels of prolactin in the body can be observed and by somefor other physiological reasons. So, the increase in the level of this hormone in the body can be associated with increased physical exertion, the "prolactin burst" can accompany the sexual intercourse and be observed for some time after its completion, the prolactin level increases and with the stimulation of the nipples.

But if such states are "coming and going", then some other factors that cause the increase in prolactin levels can very much prevent a woman from acquiring a long-awaited offspring. After all, constant elevated concentrations of prolactin in the female body suppress the normal formation and development of the follicle, thereby preventing the conception of the baby, and then the doctors can diagnose hormone infertility. But here to panic about this at once and finally, at the same time, do not advise: with adequate reaction and intervention of specialists hyperprolactinaemia - namely the so-called state, in which constant elevated levels of prolactin in the body are fixed - is successfully treated.

Causes and symptoms of hyperprolactinemia

About the physiological causes of a condition such as hyperprolactinaemia, which is accompanied by an excess of prolactin in the body, we have already mentioned. Among such reasons - increased physical activity, intimate process and postorgazmichesky period, the effect on the female nipples through caresses. Several elevated levels of prolactin may be after a period of sleep. It should also be taken into account that prolactin is extremely sensitive to emotional changes, primarily to stressful situations: against a background of chronic stress, the concentration of the hormone is significantly increasing, which can also have a negative impact on the possibility of conception.

Much worse if hyperprolactinaemia is associated with other, much more serious physiological disorders and diseases. To the pathological conditions capable of provoking persistent elevated levels of prolactin in the body and interfering with normal conception, the specialists refer to a pituitary tumor (micro- and macro-prolactinomas); polycystic ovary; gipoterioz; kidney and liver diseases, some other diseases.

In addition, hyperprolactinemia may be due to the use of certain hormonal medications, for example, contraceptive, psychotropic, antihypertensive, antiemetic, tranquilizers. On the development of prolactin, some surgical interventions, in particular, curettage of the uterine cavity, surgery (or trauma) on the chest, mammary glands. To suspect of hyperprolactinemia, a woman can for quite specific symptoms, among which the most striking will be the so-called galactorrhea - involuntary and independent separation of the colostrum from the mammary glands. As a rule, accompanied by hyperprolactinemia and menstrual cycle problems: with increased levels of prolactin, the monthly can become irregular, often menstruation is completely absent for a surprisingly long period, and discharges are characterized by scarcity. In parallel, the appearance of non-typical acne or excess hair can not be observed. And against the backdrop of all this - the decline and decay of libido.

Diagnosis and necessary tests

With the appearance and "prosperity" of all the above symptoms, or separately, it makes sense to go to a doctor's consultation and take the necessary tests to determine the levels of prolactin in the body. Diagnosis in this case will provide doctors endocrinologist or gynecologist-endocrinologist, who will first take the woman's blood for analysis.

The blood for a correct result is always given in the morning on an empty stomach, 2-3 hours after awakening. At the same time, blood sampling should be prepared the day before - the day before the test, you should refrain from going to the sauna or bath, exclude alcohol, avoid stress and not practice sex. In addition, for 1-2 hours before blood sampling it is also necessary to give up smoking, since the intake of nicotine in the body also affects the concentration of prolactin.

Note that the levels of the hormone in the body can fluctuate depending on the menstrual cycle, therefore, as a rule, analyzes are given in the first and second phase to obtain the complete picture. Moreover - the norms of prolactin will depend on the specific laboratory in which the woman gives the analysis, because in each laboratory different reagents are used to determine the concentration of prolactin. In this connection, the woman can not independently decipher the testimony: in each individual case the specialist interprets the results according to the table available at his disposal.

Treatment of hyperprolactinemia

Even if you have been diagnosed with hyperprolactinaemia after all the necessary tests, you should not despair ahead of time. Especially, if the levels of prolactin are raised slightly: with adequate treatment, a successful outcome of treatment will be achieved by 80%. Although, of course, therapy can last for a long time: depending on the degree of complexity and the causes of hyperprolactinaemia, medication can last from 2 months to 2 years.

Everything is much more serious if hyperprolactinemia is associated with a pituitary tumor, even though neoplasms should not be a reason for hysterics. In time, certain prolactinomas can be eliminated with chemo- or radiotherapy, possibly with the use of suitable medication. Even tumors in most cases are successfully treated due to medical therapy, which minimizes the need for surgical intervention. Although, of course, the need for surgical intervention, too, can sometimes be necessary, and then it will be relevant to find a competent qualified neurosurgeon.

In any case, if you find hyperprolactinemia "put a cross" on pregnancy before the time can not be in any case. The main thing is to comply with all the doctor's recommendations, strictly follow the prescribed treatment and be sure to monitor your health and well-being. And then the positive outcome will not keep you waiting, and after a couple of years - you'll see - you will already sing the lullabies above the crib of the long-awaited and ardently beloved baby!

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